Abstract

Landau-Kleffner syndrome is an epileptic childhood syndrome and is synonymous with acquired epileptic aphasia. Since 1957, when Landau and Kleffner identified six children with the disorder, more than 350 cases worldwide have been reported. The specificity of Landau Kleffner syndrome is an acute loss of speech and language in a child who developed normal language and global regression of behaviour. The rarity of this syndrome makes it extremely demanding to diagnose. It requires a multidisciplinary treatment by specialists in the field of pediatrics, neuropediatrics, child psychiatry, psychology, logopedia, otorhinolaryngology, and brain imaging. The final diagnosis is based on an epileptogenically altered EEG finding during sleep with an orderly brain MRI finding, along with clinical manifestations of the syndrome. This paper describes a multidisciplinary treatment, early initiation of treatment, and further course of illness.